There's no secret what wins games: experience, talent, depth. If you have those 3 things, you'll win almost every game. Look at your National Title game participants last year. Duke and Wisconsin both had a guy who was a key rotation player early in the year (Sulaimon and Jackson) who was a non-factor in the Tournament due to different circumstances. How'd they make it that far without them? They had experience, talent, and depth.
Purdue has those things this year. Wisconsin doesn't have them this year, that's why they lost to a nobody tonight. A lot of team's will have to deal with injuries and suspensions. When Purdue has to deal with those, their replacements will be better than other teams. Every team's starters will get tired. When Purdue's starters get tired, their subs will be better than other teams. It's not hard to rank teams just by their experience, talent, and depth. Purdue will be in the neighborhood of 30 wins.