I think there have been a few conversations concerning trying things...different defenses and/or different people. In many of those conversations comments discussed how quickly the game is and how a two minute stretch can be the difference in a game. I think THIS is lost on a few and in "fairness" the flip side is that a two minutes stretch of trying things "could" be a positive difference as well. So, what is witnessed in practice and the soundness of approaches? Anyway, the knife can cut both ways...but do want to point out how the game can be decided by a run... 
Around the 2:56 mark for a few seconds https://purdue.rivals.com/news/purdue-rolls-past-penn-state-in-advance-of-extended-road-swing
Around the 2:56 mark for a few seconds https://purdue.rivals.com/news/purdue-rolls-past-penn-state-in-advance-of-extended-road-swing
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