While this is by no means an excuse, we as fans rarely give Purdue a favorable environment away from Mackey. It's amazing to me how Purdue fans can be so supportive at home throughout a season, then they go on the road and they disappear.
In Indianapolis, Purdue has fans at the Crossroads Classic, but not as many as one would expect a major state school 60 miles away. Look at our record.
In the Big Ten Tournament, it's typically in Chicago/Indy - 2 and 1 hours away from campus, respectively. Usually not a dominant crowd there. I went to the tournament this year in DC and Purdue had nowhere close to the most number of fans - as the #1 seed. It's not like Purdue's any further away really than Michigan, who had more fans than us.
In the NCAA Tournament, we used to fill up arenas - I remember taking over Rupp Arena. Sometimes you just aren't in friendly areas - playing in Spokane, that's tough to create a home court advantage. But Milwaukee is 3.5 hours away from campus, an hour from Chicago which has a massive number of alumni. There's no reason Iowa State fans should dominate our fans. Can it be 60/40, sure. But this game will probably be in the 70-80/30-20 range.
A home court advantage surely does not guarantee a win, but it also sure as hell doesn't hurt. We have not typically done that though.